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O-HEALTH: Scalable systems modelling to simulate body-level interplays among non-communicable diseases (2022-2027)

O-HEALTH: Scalable systems modelling to simulate body-level interplays among non-communicable diseases (2022-2027)

O-Health

O-Health proposes a scalable ecosystem of multiscale non-communicable disease (NCD) models that affect mechanosensitive organs. The NCD models will be interrelated among each other through a body-wide systemic model of low-grade inflammation, to explore the subclinical phases of NCD development. The project tackles four major NCD: lung emphysema, atherosclerosis, intervertebral disc degeneration and knee osteoarthritis that affect the body at different anatomical locations. The O-health ecosystem will be modular and interoperable.

Funding Programme: European Research Council (ERC)

Instrument: ERC Consolidator Grant

Role: Individual project

Dates: 2022-2027

Investigadores principales

NOALLY, Jérôme